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The Middle East has been plunged into a new era of volatility afterjoint U.S.-Israeli strikeson Iran since Feb. 28 have reportedlykilled more than 1,000 people, includingmore than 150 schoolchildren, and triggered a wave of Iranian retaliatory attacks across the region.
Iran's Supreme Leader Ayatollah Ali Khamenei and dozens of senior Iranian officials have been killed in the strikes, leaving a power vacuum in Tehran. The fate of Iran's theocratic government is uncertain, and the Trump Administration has openly called for regime change. The strikes also collapsed nascent U.S. talks with Iran over the future of their nuclear program, which were earlier derailed by the12-day warbetweenIran and Israellast June.
"We're doing this, not for now, we're doing this for the future, and it is a noble mission," President Donald Trump said in a video statement after launching the attack, dubbed "Operation Epic Fury." He warned of potential American casualties—"that often happens in war," he said—andseveral U.S. servicemembershave already been killed in the days since.
The spiraling conflict has also endangered millions of lives across the Middle East and left tens of thousands of foreign citizens stranded and at risk of being caught in the violence in the region. Its effects are also felt globally on the economy, having disrupted one of the world's most important energy corridors as well as a key hub of the aviation and tourism sectors.
Here's what to know about how the U.S. and Israeli war with Iran got to this point and what could come next.
Why did the U.S. and Israel strike Iran?
American and Israeli officials haveoffered conflicting explanationsfor why they attacked Iran, even as Trump has insisted that strikes were necessary and that operations would continue until U.S. objectives are met. Immediately after the launch of "Operation Epic Fury" on Feb. 28, Trumpcharacterizedthe attack as defensive and suggested that it was intended to eliminate "imminent threats" from Iran. Israeldescribedit as a "preemptive strike" aimed at neutralizing an anticipated missile attack from Iran. Trump had a "good feeling" that Iran was planning to attack the U.S., White House Press Secretary Karoline Leavitttoldreporters on March 4. Neither the U.S. nor Israel provided evidence that Iran was planning to attack them. In private briefings to Congress, Trump Administration officialsacknowledgedthat U.S. intelligence did not show Iran was preparing to strike before the U.S.-Israeli attacks; instead, they said Iran's missiles and proxy forces posed a threat to U.S. personnel and allies in the region, although officials presented differing views over whether that threat was more general or imminent.
The rationale behind the strikes continued evolving days after the strikes. U.S. officials havedescribed the offensiveas aimed at crippling Iran's ballistic missile infrastructure and preventing Iran fromobtaining a nuclear weaponafter what the Trump Administration has sincesaidwere failed nuclear negotiations. Israeli Prime Minister Benjamin Netanyahu has repeatedly described the Iranian regime as an "existential threat" to Israel. Iran has maintained that it isnot looking to developa nuclear weapon, although the United Nations' nuclear watchdog said Tehran had enriched uranium beyond civilian energy needs. Even so, the watchdog said that Iran did not have a structured program towardsdeveloping a nuclear weapon. After bombing three Iranian nuclear facilities last June, Trump alsoclaimedthat the U.S. had "obliterated" Iran's nuclear program.
Amirhossein Khorgooei—ISNA/AFP/Getty Images" style="max-width:100%; height:auto; border-radius:6px; margin:10px 0;" loading="lazy" /> U.S. Secretary of State Marco Rubio initially suggested that the U.S. launched strikes in part due to pressure from Israel which was preparing its own attack. Rubio, as well as Trump, laterwalked back those comments, insisting that the strike was a decision made by Trump and that Israel did not force U.S. action.
Defense Secretary Pete Hegsethsaidthat the operation is "not a so-called regime change war," but broader American and Israeli messaging have indicated a goal of toppling Iran's leadership. Immediately after the strikes, Trumpcalled onthe Iranian people to "take over" their government. The strikes also came weeks after Trump hadpromised to "rescue"Iranian protesters in January. After Khamenei's killing, Israel warned that whoever became the next Supreme Leader under the current regimewould also be a potential target.
What is the relationship between the U.S. and Iran?
The U.S. and Iran have long been political adversaries, ending formal diplomatic ties after the 1979 Iranian Revolution which established the Islamic Republic of Iran. During Trump's second term in office, the Trump Administration hasramped up pressureon Iran to abandon its nuclear program after Trump in his first termwithdrew the U.S.from a nuclear deal the Barack Obama Administration agreed with Iran. In January, Trump also threatened the Iranian regime over itsviolent crackdownon anti-government protesters.
Even so, Washington and Tehran had been engaged in ongoing nuclear negotiations when the U.S. and Israel carried out its strikes. Those talks had resumed in early February after being stalled since June, whenIsrael attacked Iranand theU.S. joined Israel in strikes on Iranian nuclear sites. There were reports of limited but notable progress between U.S. and Iranian negotiators, who met inOmanon Feb. 6 andGenevaon Feb. 26 and 27, just a day before the U.S.-Israeli strikes. The ongoing attacks, however, have once again hardened Iran's stance towards the U.S. and may have shattered hopes for adiplomatic agreement around Iran's nuclear program.
How has Iran responded?
Iran responded with a swathe of retaliatory attacks on U.S. military installations across the region, hitting Israel, United Arab Emirates, Qatar, Bahrain, Kuwait, and Saudi Arabia in initial attacks over the weekend. Suspected Iranian strikes have alsohit civilian sites, including Saudi Arabia'soil refinery, ahotel in Dubai, and near airports in the U.A.E. and Kuwait. In the following days, Iran expanded its attacks, launching missiles and drones at Jordan which were intercepted andtargeting a British Royal Air Force base in Cyprus. Suspected Iranian strikes have also been reported over Iraq and Oman's airspace. Iran also begantargetingAmerican political centers in the region, including striking U.S. embassies in Riyadh and Kuwait City.More than a dozen peoplehave been killed by suspected Iranian strikes across the region.
AFP/Getty Images" style="max-width:100%; height:auto; border-radius:6px; margin:10px 0;" loading="lazy" /> Six U.S. service members were killedin an Iranian retaliatory strike on a U.S. operations center in Kuwait, marking thefirst reported American combat deathsin this war. More than a dozen other soldiers were reportedly wounded in Iranian attacks.
Iran's conventional military capabilities are far smaller and less technologically advanced than those of the U.S. and Israel. Iran has more than600,000 active military personnel, with another 350,000 reserves, compared toIsrael's roughly 170,000 active-duty personneland more than 450,000 reservists. But ataround $10 billion, Iran's defense budget is dwarfed byIsrael's $35 billion budget, not to mention the U.S.'s nearly$1 trillion defense budget—the largest in the world. Israel also has highly advanced missile defense systems and is believed to possess a clandestine nuclear weapon, while the U.S. has one of the biggest nuclear arsenals in the world, superior technology, and extensive military reach across the world. Experts toldAl Jazeerathat Iran has shifted its strategy since last June toward a more aggressive use of regional missiles and drone attacks, although it is still constrained by its degraded capabilities and fear of escalating war with the U.S.
The conflict has also broadened after Iranian-backed paramilitary Hezbollah fired rockets and drones at an Israeli military site on March 2 in retaliation for Khamenei's killing. Israel responded with ongoing strikes on Beirut and southern Lebanon which havekilled more than 50 peopleas it continues to trade attacks with Hezbollah. Lebanon has condemned both Israel and Hezbollah's attacks and urged them not to use Lebanon as a "platform for proxy wars."
How has the rest of the world reacted?
Immediately after the first wave of American and Israeli strikes in Iran, world leaders urgedrestraint, and multilateral institutions like theUnited Nationsand theEuropean Unionhave called for de-escalation.
The Gulf States have historically avoided direct confrontation with Iran and repeatedly rejected being dragged into a regional conflict. In the weeks leading up to the U.S. attack, Oman had been mediating indirect talks between Washington and Tehran. But as neighboring states found themselves in Iran's crosshairs after Tehran targetedU.S. basesand civilian sites across the region, the Gulf Cooperation Council, which includes the UAE, Bahrain, Saudi Arabia, Oman, Qatar, and Kuwait,convenedan emergency meeting to condemn Iran's actions and "reserve[d] their legal right to respond."
The North Atlantic Treaty Organization, of which the U.S. is a member, supports the military campaign against Iran, according to itssecretary-general Mark Rutte, although the alliance said itwill not get involved. Some of the U.S.'s NATO allies have shown hesitation over being dragged into the war. The U.K. initially opposed the U.S. military using a joint base in the British-governed Chagos Islands to send defensive missiles to Iran, but Prime Minister Keir Starmer eventuallyrelentedfollowing public rebuke by Trump. Starmer alsoallowedthe U.S. to use its military base RAF Akrotiri in Cyprus for "defensive" strikes against Iran; the base was hit in asuspected Hezbollah drone strikesoon after the announcement. Spain was more resolute: when Trump threatened to cut off bilateral trade after the European nation rejected the American military's use of its bases, its Prime Minister Pedro Sánchezresponded, "No to war."
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Outside the Middle East, the conflict has prompted warnings of a greater global fallout.Indiahas raised concerns about knock-on effects, including to trade and energy supply chains, whileRussia, Iran's ally that has pinned blame on the U.S. and Israel andremains at war with Ukraine, condemned the new violence as pushing the region "toward a humanitarian, economic, and potentially even radiological disaster."
What are the global implications of the war?
The war has caused widespread travel disruption. While Americans have beenadvised to leave the Middle East immediately, doing so is not easy: several Gulf nations closed their airspaces, and some international airports in the Gulf, many of which serve as key transit points for global travel, also sustained damage from Iran's counteroffensives, leaving thousands of travelers stranded. Some Gulf airlines have since resumed flights, though mainly forrepatriationefforts.
The war alsothreatens to disrupt global oil and natural gas supplies. There is already a bottleneck in theStrait of Hormuz, a narrow maritime passage between the Persian Gulf and the Gulf of Oman through which around a fifth of the world's oil production passes. Iran, which controls the northern side of the strait and can block any traversing ships, has previously used the waterway as a political bargaining chip amid tensions. Following the attack over the weekend, Iranian forces threatened that any ship passing through would be "set ablaze." Several LNG facilities across the region were also attacked. Analyststold TIMEthat the threat of prolonged conflict has prompted shippers to either dock to avoid risks or to jack up costs, leading to price surges.
Read More:After Khamenei: What Iran, and the World, Face Next
Who was Ayatollah Ali Khamenei?
Ayatollah Ali Khamenei had served as Iran's Supreme Leader for more than 36 years, the longest of any leaderin the Middle Eastat the time of his death. Like Ruhollah Khomeini, the grand ayatollah who founded the Islamic Republic of Iran after the 1979 revolution, Khamenei strongly rejected what the theocratic regime saw as "Western imperialism," positioning Iran as a counterweight to American, Israeli, and Saudi influence in the region. Under Khamenei's rule, Iran funded militant groups, including Hezbollah, to function as regional proxies.
As Supreme Leader, Khamenei virtually dictated all aspects of governance in the Islamic Republic, appointing the heads of the judiciary and controlling Iran's military and the Revolutionary Guard Corps—the defenders of Iran's Islamic system. Khamenei often used the broad range of powers at his disposal to quell dissent.
Read More:Ali Khamenei, Iran's Supreme Leader Who Built a De Facto Military Dictatorship, Killed in U.S.-Israeli Strikes
Rouzbeh Fouladi—Middle East Images/AFP/Getty Images" style="max-width:100%; height:auto; border-radius:6px; margin:10px 0;" loading="lazy" /> Khamenei's detractorsrejoiced upon hearing his death, citing decades of repression and crackdowns on expression and protests under his rule. In 2022,protests broke outafter the death of Mahsa Amini in the custody of so-called "morality police" for allegedly flouting Hijab laws, only for the Khamenei regime to respond witheven more stringent punishmentsto deter women from breaching strict dress code rules. People also took to the streetslate last year and early this yearto vent their frustration at Iran's struggling economy amid a plunging currency and soaring inflation, issues that stem in part from international sanctions imposed on Iran over the years.
Who will likely succeed Khamenei as leader?
With Khamenei's antagonistic views towards the U.S. and the West, his death has sparked hope for a more moderate or reformist Supreme Leader to take his place. But thepool of replacement candidateshas also become significantly smaller in recent years, especially as the U.S. has killed some of Khamenei's preferred successors. Trump has said Iran needs "more moderate" leadership, but he conceded that in the worst case, Khamanei's replacement could be someone "who's as bad as the previous person." The attacks have tested Tehran's willingness to negotiate with Washington.
Iran's constitution states that the Supreme Leader must be a Shia Islamic jurist chosen by the Assembly of Experts, an 88-member elected committee of clerics. Among the possible candidates to replace Khamenei are his son Mojtaba Khamenei; Supreme Court Chief Justice Gholam-Hossein Mohseni-Eje'i; and Hassan Khomeini, the grandson of former Supreme Leader Khomeini.
What's the legal status of the war?
Lawmakers and international observers have raised concerns about the legal basis for the U.S.-Israeli strikes. While the U.S. President is also the country's Commander in Chief, his authority to order military action is limited to repelling attacks or deterring a clearly imminent attack, an experttoldTIME, and so far there has been little evidence that is the case. For the President to launch an attack on a sovereign state, he is required to get authorization from Congress, which has the exclusive power to declare war. Military action without congressional approval is restricted by the 1973 War Powers Resolution, which limits the operation to 60 days.
Although Congress does not need to take action to declare the strikes illegal, lawmakers have again found their abilityto constrain Trumplimited, especially after military action has already been taken. Democrats in the Senate attempted to block further military action against Iran without congressional authorization, but theresolution failed. Another war powers resolution is expected to be voted on in the House on March 5. Trump has largely been able to carry out military action without congressional approval or significant recourse, including themilitary raid on Venezuela,strikes on alleged drug boatsin the Caribbean and Pacific, andstrikeson several countries, including Iran.
Read More:Did Trump Have the Legal Authority to Strike Iran? An Expert Explains
How long could the war last?
Trump hasoffered conflicting timelineson how long the Iran conflict will take to resolve. Early on Feb. 28, after the initial strikes, he toldAxiosthat he had the choice to "go long" or "end it in two to three days." The day after the first salvo, Trump toldthe Daily Mailthat the campaign in Iran would take about four weeks.
In a March 2 Pentagon press briefing, Chairman of the Joint Chiefs Gen. Dan Caine said the campaign was "not a single overnight operation," and Defense Secretary Pete Hegseth said that the Administration would "never hang a time frame" on the war and that the progress could "move up" or "move back."
What do Americans think of the war?
Several polls carried out in the immediate days after the U.S.-Israeli attack suggest that most Americans disapprove of the war, although sentiment towards the war has been divided along party lines. According to most polls, most Republicans support the military action, while most Democrats and Independents do not.
Andrea Ronchini—NurPhoto/Getty Images" style="max-width:100%; height:auto; border-radius:6px; margin:10px 0;" loading="lazy" /> Across the board, 69% of Americans, according to aCBS News poll, said Trump needs to get authorization from Congress to continue military operations against Iran. A majority of those surveyed also felt the Trump Administration had not provided a clear explanation for the U.S.'s objectives in Iran.
Read More:How Americans Feel About Trump's War With Iran, According to the Latest Polls
Across American cities, people have also taken to the streets to protest the war, including in New York City, Los Angeles, Miami, Chicago, and D.C. At the same time, thousands of others haveralliedto celebrate the death of Khamenei and call for the end of the Iranian regime.
Contact usatletters@time.com.
Smoke rises following an explosion, 
Smoke rises following an explosion after the U.S. and Israel reportedly launched an attack against Iran, in Tehran, Iran, February 28, 2026, in this screen grab taken from video." style="max-width:100%; height:auto; border-radius:6px; margin:10px 0;" loading="lazy" /> 
A plume of smoke rises following a reported explosion in Tehran on February 28, 2026. Two loud blasts were heard in Tehran on February 28 morning by AFP journalists, and two plumes of thick smoke were seen over the centre and east of the Iranian capital. 
U.S. President Donald Trump pumps his fist after disembarking Air Force One at Palm Beach International Airport in West Palm Beach, Florida, U.S., February 27, 2026. Hours later, Trump made live comments about the military strikes he launched against Iran." style="max-width:100%; height:auto; border-radius:6px; margin:10px 0;" loading="lazy" /> 
Buildings inin Tehran stand after Israel and the U.S. launched strikes on Iran, February 28, 2026." style="max-width:100%; height:auto; border-radius:6px; margin:10px 0;" loading="lazy" /> 
Children run to an underground shelter amid reports of incoming missiles on February 28, 2026 in Tel Aviv, Israel. 
A man carries two children as he runs to take shelter after sirens sounded in Tel Aviv on February 28, 2026, following the announcement that Israel had launched a "preemptive strike" on Iran. 
People run to take shelter after sirens sounded in Tel Aviv on February 28, 2026, following the announcement that Israel had launched a "preemptive strike" on Iran. President Donald Trump urged Iranians on February 28 to take over their government as US forces began a large-scale attack on the country's military." style="max-width:100%; height:auto; border-radius:6px; margin:10px 0;" loading="lazy" /> 
Patients are placed in a parking lot at Sourasky Medical Center for safety after sirens sounded in Tel Aviv on February 28, 2026, following the announcement that Israel had launched a "preemptive strike" on Iran. 
